BDBM50558174 CHEMBL4787638
SMILES Clc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
InChI Key InChIKey=LUPOAJYFMCPOHX-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50558174
Affinity DataIC50: 2.32E+5nMAssay Description:Inhibition of human liver microsomes CYP2C9 using diclofenac as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 142(Mus musculus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.34E+6nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 bindingMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+5nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair