BDBM50560477 CHEMBL4742906
SMILES Cc1cc(-c2cnc3cc(ccn23)-c2ccc(cc2)C2CNCCN2)c2ccccc2n1
InChI Key InChIKey=UQEFQNWFVJXGDE-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50560477
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 192nMAssay Description:Inhibition of human ALK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BMPR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.59E+3nMAssay Description:Inhibition of human TGFBR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 9.35E+3nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of human ALK5 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair