BDBM50564922 CHEMBL4789481

SMILES Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C(=O)NO)ccc2n(C)c1=O

InChI Key InChIKey=AXJXDWNCHLEVAZ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564922   

TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564922(CHEMBL4789481)
Affinity DataIC50:  797nMAssay Description:Inhibition of recombinant human HDAC1 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeregrin(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564922(CHEMBL4789481)
Affinity DataKd:  175nMAssay Description:Binding affinity to BRPF1 (unknown origin) by Isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564922(CHEMBL4789481)
Affinity DataIC50:  908nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564922(CHEMBL4789481)
Affinity DataIC50:  344nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed