BDBM50566079 CHEMBL4793685

SMILES c1ccc(cc1)-c1cccc2ccncc12

InChI Key InChIKey=RPKRABUEPOPVDF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566079   

TargetTumor necrosis factor(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566079(CHEMBL4793685)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of probe-5 binding to human TNFalpha (77 to 233 residues) at 1 nM by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566079(CHEMBL4793685)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed