BDBM50566263 CHEMBL4776653

SMILES Nc1cc(cnc1C(=O)NC[C@@H](O)C(F)(F)F)S(=O)(=O)c1ccccc1OC(F)(F)F

InChI Key InChIKey=PLVUVNNMEKGPMZ-GFCCVEGCSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50566263   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566263(CHEMBL4776653)
Affinity DataEC50: <0.310nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed