BDBM50567666 CHEMBL4850615

SMILES COc1ccc(cc1)-c1nc2n(nc(-c3ccccc3)c2c(-c2ccc(cc2)N2CCN(C)CC2)c1C#N)-c1ccccc1

InChI Key InChIKey=MMYWILWEDPWJHZ-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50567666   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataKi:  40nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) after 10 mins by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataKi:  127nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataKi:  144nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataKi:  5.69E+4nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataIC50:  209nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataIC50:  225nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567666(CHEMBL4850615)
Affinity DataIC50:  67nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) after 10 mins by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed