BDBM50574819 CHEMBL4860770

SMILES Cc1ccc(C[C@H](NC(=O)c2ccc3OCCOc3c2)C(=O)N[C@@H](CCc2ccccc2)\C=C(/F)S(=O)(=O)Oc2ccccc2)cc1

InChI Key InChIKey=AWPGRJIMHKDGDB-VFCIBZHASA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50574819   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574819(CHEMBL4860770)
Affinity DataKi:  7nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574819(CHEMBL4860770)
Affinity DataKi:  39nMAssay Description:Inhibition of human CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric enzyme assaysMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574819(CHEMBL4860770)
Affinity DataKi:  98nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574819(CHEMBL4860770)
Affinity DataKi:  348nMAssay Description:Inhibition of human liver CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorometric enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed