BDBM50575484 CHEMBL4847272

SMILES N[C@H](CC(O)=O)Cn1nnc(n1)-c1ccc(Oc2ccc(cc2)-c2ncco2)cc1

InChI Key InChIKey=JVHCOXOIUBKBEW-OAHLLOKOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575484   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575484(CHEMBL4847272)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575484(CHEMBL4847272)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]WIN35428 from recombinant human dopamine transporter by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575484(CHEMBL4847272)
Affinity DataIC50:  141nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed