BDBM50575612 CHEMBL4856184
SMILES COc1cc2c(NCC3CCN(Cc4ccc(cc4)C(=O)NO)CC3)cc(nc2cc1OCCCN1CCCC1)-c1ccc(C)o1
InChI Key InChIKey=JKEZOPHKGXCQKI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50575612
Affinity DataIC50: 524nMAssay Description:Inhibition of full length human C-terminal His-tagged/C-terminal Flag-tagged HDAC1 using fluorogenic acetylated peptide as substrate incubated for 30...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University Of Navarra
Curated by ChEMBL
University Of Navarra
Curated by ChEMBL
Affinity DataIC50: 167nMAssay Description:Inhibition of human DNMT1 enzyme using polydeoxy-inosine polydeoxy-cytosine DNA as substrate incubated for 15 mins in presence of SAM by TR-FRET assa...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Navarra
Curated by ChEMBL
University Of Navarra
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human G9a enzyme using histone monomethyl-H3K9 peptide as substrate incubated for 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of full length human N-terminal GST-tagged HDAC6 using fluorogenic acetylated peptide as substrate incubated for 30 mins by fluorescence p...More data for this Ligand-Target Pair