BDBM50582302 CHEMBL5072152

SMILES CNCCNC(=O)c1cccn2c1nc1c3ccccc3ccc1c2=O

InChI Key InChIKey=IRKGQXHMYKLWGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582302   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582302(CHEMBL5072152)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582302(CHEMBL5072152)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582302(CHEMBL5072152)
Affinity DataIC50:  470nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed