BDBM50582305 CHEMBL5091818

SMILES O=C(NCCN1CCCC1)c1cccn2c1nc1c3ccccc3ccc1c2=O

InChI Key InChIKey=NYGRZGUFWCNCCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582305   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582305(CHEMBL5091818)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582305(CHEMBL5091818)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582305(CHEMBL5091818)
Affinity DataIC50:  210nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed