BDBM50584073 CHEMBL5081219
SMILES O\N=C(/Nc1ccc(F)c(Cl)c1)c1cnc(Cl)s1
InChI Key InChIKey=YEHPORMCSRDVNM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50584073
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of human IDO1 protein assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate by methylene blue reagent base...More data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human TDO2 protein assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 1 hr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 48nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair