BDBM50585759 CHEMBL5081712

SMILES CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3ccccc3)cc2n1

InChI Key InChIKey=MLZPRAPIZUZUNO-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585759   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585759(CHEMBL5081712)
Affinity DataIC50:  18nMAssay Description:Inhibition of full length N-terminal GST tagged human CDK2(1 to 298 residues)/CyclinA2 (1 to 432 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585759(CHEMBL5081712)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of full length N-terminal GST fused human CDK5(1 to 292 residues)/ p25 (99 to 307 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed