BDBM50585779 CHEMBL5088595
SMILES CCc1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cn1
InChI Key InChIKey=QXVWBJROURLRIW-HSZRJFAPSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50585779
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length N-terminal GST fused human CDK5(1 to 292 residues)/ p25 (99 to 307 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of full length N-terminal GST tagged human CDK2(1 to 298 residues)/CyclinA2 (1 to 432 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
Affinity DataIC50: 223nMAssay Description:Inhibition of full length N-terminal GST fused human CDK9(1 to 372 residues)/ His- tagged CyclinT1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Goldfinc Bio
Curated by ChEMBL
Goldfinc Bio
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Inhibition of full length N-terminal GST fused human CDK7 (1 to 346 residues)/CyclinH (1 to 323 residues)/ MAT1 (1 to 309 residues) expressed in bacu...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Goldfinc Bio
Curated by ChEMBL
Goldfinc Bio
Curated by ChEMBL
Affinity DataIC50: 235nMAssay Description:Inhibition of full length N-terminal GST fused human CDK6 (1 to 326 residues)/CyclinD3 (1 to 292 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair