BDBM50589650 CHEMBL5202961

SMILES COc1cc(OCC(=O)Nc2cc(OC(F)(F)F)ccc2-n2cncn2)ccc1OC1COC1

InChI Key InChIKey=KGZJVSVIUHWKQW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50589650   

TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  813nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  819nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed