BDBM50590269 CHEMBL5187963

SMILES Cc1cccc2c1nc(CSc1ncccn1)[nH]c2=O

InChI Key InChIKey=ANAUZAZPUGQDNM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50590269   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  800nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  200nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  800nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed