BDBM50590270 CHEMBL5181770
SMILES Cc1cc(Br)cc2c1nc(CSc1ncccn1)[nH]c2=O
InChI Key InChIKey=UYAVGZOEYLNVKI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50590270
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair