BDBM50594527 CHEMBL5177921

SMILES C=CC(=O)N1CCC(CC1)(c1nnn[nH]1)c1ccccc1

InChI Key InChIKey=DDLXRXJBUKYUPA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50594527   

TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of GST-tagged human MLL1 (1147 to 1203 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMethylcytosine dioxygenase TET1(Homo sapiens)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of GST-tagged human TET1 (583 to 633 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMethylcytosine dioxygenase TET3(Homo sapiens)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of GST-tagged human TET3 (49 to 68 residues) expressed in Escherichia coli BL21 cell incubated for 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
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TargetCXXC-type zinc finger protein 5(Homo sapiens)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of GST-tagged human CXXC5 (255 to 305 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetLysine-specific demethylase 2B(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of GST-tagged human KDM2B (604 to 660 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCXXC-type zinc finger protein 4(Homo sapiens)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of GST-tagged human IDAX (130 to 181 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
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TargetF-box/LRR-repeat protein 19(Homo sapiens)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-tagged human FBXL19 (31 to 86 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of GST-tagged human KDM2A (562 to 618 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed