BDBM50595596 CHEMBL5203670

SMILES CCCc1cc(=O)[nH]c(SCC(=O)c2ccc3NC(=O)CCCc3c2)n1

InChI Key InChIKey=WVRKQDZPZOUPNW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50595596   

TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595596(CHEMBL5203670)
Affinity DataIC50:  470nMAssay Description:Inhibition of human recombinant AKR1C1 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595596(CHEMBL5203670)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595596(CHEMBL5203670)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant AKR1C3 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595596(CHEMBL5203670)
Affinity DataIC50:  730nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxi...More data for this Ligand-Target Pair
In DepthDetails PubMed