BDBM50595766 CHEMBL5171054

SMILES COc1ccc(C)cc1C1(CC1c1cccc(OC(C)C)n1)C(=O)NS(=O)(=O)c1cccc2nc(C)ccc12

InChI Key InChIKey=WYIZSZVJNIHVCJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595766   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595766(CHEMBL5171054)
Affinity DataEC50:  0.900nMAssay Description:Modulation of homozygous F508del/F508del CFTR mutant in HBE cells incubated for 18 to 24 hrs by trans-epithelial current clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed