BDBM50595815 CHEMBL5179962
SMILES CNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N([C@@H]2CCC[C@@H](O)C2)C(=O)C32CC2)cc1
InChI Key InChIKey=AKQOBHZKBDHWQI-HUUCEWRRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50595815
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
Affinity DataIC50: 642nMAssay Description:Inhibition of CDK2 in human COV318 cells incubated for overnight in presence of human whole blood by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of CDK2 in human COV318 cells incubated for overnight in presence of human whole blood by HTRF assayMore data for this Ligand-Target Pair