BDBM50596981 CHEMBL5186476

SMILES Fc1cc(F)c(OCc2cccnc2F)c(c1)C1CC1NCC(=O)N1CCC2(CCNC2)CC1

InChI Key InChIKey=AOUYVKAMPAJOPE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596981   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596981(CHEMBL5186476)
Affinity DataKi:  220nMAssay Description:Inhibition of human LSD1 assessed as inhibitory constant using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596981(CHEMBL5186476)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human LSD1 assessed as demethylase activity of LSD1 using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed