BDBM50596984 CHEMBL5207485

SMILES Fc1cc(F)c(OCc2cccnc2F)c(c1)[C@H]1C[C@@H]1NCC(=O)N1CCC2(CCNC2)CC1

InChI Key InChIKey=AOUYVKAMPAJOPE-NQIIRXRSSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596984   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596984(CHEMBL5207485)
Affinity DataKi:  80nMAssay Description:Inhibition of human LSD1 assessed as inhibitory constant using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596984(CHEMBL5207485)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of MAO-B (unknown origin) using tyramine as substrate and measured after 10 mins by peroxidase-coupled reaction methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596984(CHEMBL5207485)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine as substrate and measured after 10 mins by peroxidase-coupled reaction methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596984(CHEMBL5207485)
Affinity DataIC50:  390nMAssay Description:Inhibition of human LSD1 assessed as demethylase activity of LSD1 using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails PubMed