BDBM50598895 CHEMBL5172829

SMILES CCOc1ccc2[nH]c(Cc3nc4n(CC)c(=O)[nH]c(=O)c4n3Cc3ccccc3)nc2c1

InChI Key InChIKey=CPISMKNBAXDQEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598895   

TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM50598895(CHEMBL5172829)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-terminal MBP-tagged full length human TPH2 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM50598895(CHEMBL5172829)
Affinity DataIC50:  850nMAssay Description:Inhibition of N-terminal MBP-tagged full length human TPH1 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed