BDBM50599552 CHEMBL5195299

SMILES COc1cc2ccn(C\C=C\C(=O)NCc3ccccc3)c(=O)c2cc1OC

InChI Key InChIKey=OTYRMXHYDGZOQY-RMKNXTFCSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599552   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599552(CHEMBL5195299)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599552(CHEMBL5195299)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of 20S constitutive proteosome beta2c subunit (unknown origin) assessed as substrate hydrolysis using Boc-Leu-Arg-Arg-AMC as fluorogenic s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599552(CHEMBL5195299)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta1c subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed