BDBM50599750 CHEMBL5180445

SMILES FC(F)(F)c1cc(Cl)n(Cc2cc(=O)n3c([C@@H]4C[C@@H]4C#N)c(Cl)ccc3n2)n1

InChI Key InChIKey=GPMGDUIAVSFGGH-PSASIEDQSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599750   

TargetGlutamate receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599750(CHEMBL5180445)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluA2-AMPA receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599750(CHEMBL5180445)
Affinity DataEC50:  39nMAssay Description:Positive allosteric modulator activity at GluN2A receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599750(CHEMBL5180445)
Affinity DataIC50:  380nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed