BDBM50601245 CHEMBL5196139
SMILES S=c1cc(Cc2ccccn2)[nH]c2nc(Nc3c4CCCc4cc4CCCc34)nn12
InChI Key InChIKey=BHTLYBBOAZYXBF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50601245
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated human THP1-ASC-GFP cells assessed as reduction in speck positive cells measured after 30 mins in p...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated human whole blood assessed as reduction in IL-1beta release pretreated for 30 mins followed by ATP...More data for this Ligand-Target Pair