BDBM50601568 CHEMBL5178472
SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.N\C(NCCCc1cnc(N)s1)=N/C(=O)NCc1ccccc1
InChI Key InChIKey=OOWFNIJVULNJEZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50601568
Affinity DataKi: 27nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKi: 4.57E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
Affinity DataKi: 5.62E+3nMAssay Description:Displacement of [3H] mepyramine from human histamine H1 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RGS4 incuba...More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 an...More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]UR-PI294 from human histamine H3 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 and ...More data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing ARRB2 incubated for 60 mins by beta-arrestin2 recruit...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
Affinity DataEC50: 3.39E+3nMAssay Description:Agonist activity at human D2 long receptor stably expressed in HEK293T cells co-expressing ElucN-betaarr2 hD2longR-ElucC by beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Agonist activity at human D3 receptor stably expressed in HEK293T cells co-expressing ElucN-betaarr2 hD3R-ElucC by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0258nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKd: 0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
Affinity DataKd: 0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 an...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Displacement of [3H]UR-PI294 from human histamine H3 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 and ...More data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Displacement of [3H] mepyramine from human histamine H1 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RGS4 incuba...More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair