BDBM50601652 CHEMBL5191857

SMILES COCCC(=O)N[C@@H](Cc1coc2ccccc12)B(O)O

InChI Key InChIKey=DQERLKUHEUIJOF-ZDUSSCGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601652   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601652(CHEMBL5191857)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601652(CHEMBL5191857)
Affinity DataIC50:  11nMAssay Description:Inhibition of 20S immunoproteasome beta-5i subunit in human PBMC using Ac-ANW-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601652(CHEMBL5191857)
Affinity DataIC50:  241nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human A549 cells using Suc-LLVY-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601652(CHEMBL5191857)
Affinity DataIC50:  400nMAssay Description:Inhibition of human 20S proteasome beta5 subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed