BDBM50602801 CHEMBL5202420

SMILES Cc1ccc(NC(=O)c2ccc3cnccc3c2)cc1C(=O)Nc1cnc(Nc2cccc(NC3CCN(CC3)C(=O)C=C)c2)nc1

InChI Key InChIKey=JLONRANGHBAJIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50602801   

TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50602801(CHEMBL5202420)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of wild type N-terminal GST tagged BLK (unknown origin) (1 to 505 residues) expressed in sf21 insect cell using TK as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50602801(CHEMBL5202420)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of (S)-3-(3-(5-acrylamido-6-(3-(5-(2-methyl-5-(3-(trifluoromethyl)benzamido)benzamido)pyrimidin-2-ylamino)phenylamino)-6-oxohexylamino)-3-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50602801(CHEMBL5202420)
Affinity DataIC50:  58nMAssay Description:Inhibition of wild type N-terminal GST tagged BTK (unknown origin) (2 to 659 residues) expressed in sf21 insect cell using TK as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed