BDBM50604025 CHEMBL5173861
SMILES OCc1cc(ncc1-c1ccc(cc1)C1(CC(F)(F)C1)C(=O)Nc1ccc(F)cc1)C(F)(F)F
InChI Key InChIKey=BZERBBHQRWKZER-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50604025
Affinity DataIC50: 1.5nMAssay Description:Inhibition of IDO1 in IFN gamma-stimulated human HeLa cells measured after 48 hrs by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 805nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pharmaron Beijing
Curated by ChEMBL
Pharmaron Beijing
Curated by ChEMBL
Affinity DataIC50: 6.10E+6nMAssay Description:Inhibition of MK-499 binding to hERGMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of IDO1 in IFNgamma/LPS stimulated human whole blood assessed as unbound concentration using kynurenine/tryptophan as substrate preincubat...More data for this Ligand-Target Pair