BDBM50605217 CHEMBL5194638
SMILES FC(F)(F)c1ccc(Cn2ccnc2C(=O)Nc2nnc(s2)N2CCC(CC2)Nc2nnc(NC(=O)Cc3ccccc3)s2)cc1
InChI Key InChIKey=BGZTVMRSKUPCTK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50605217
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 52nMAssay Description:Binding affinity to human GLS1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Allosteric inhibition of human GLS1 using glutamine as substrate incubated for 60 mins by NADH/NADPH-based absorbance analysisMore data for this Ligand-Target Pair