BDBM50611445 CHEMBL5289396

SMILES Cc1cc(Cn2nc(cc2Cl)C(F)F)cc(=O)n1C[C@H]1C[C@@H]1C#N

InChI Key InChIKey=ZPKSTKHRFWJTKK-VXGBXAGGSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50611445   

TargetGlutamate receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50611445(CHEMBL5289396)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50611445(CHEMBL5289396)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed