BDBM50613415 CHEMBL5273872

SMILES Fc1ccc(c(F)c1)-c1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1

InChI Key InChIKey=XZCZVUKTNGBHOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613415   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50613415(CHEMBL5273872)
Affinity DataIC50:  62nMAssay Description:Inhibition of GSK-3beta (unknown origin) assessed as decrease in tau phosphorylation by high content cell based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50613415(CHEMBL5273872)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50613415(CHEMBL5273872)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed