BDBM50746 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylidene-3-pyrrolidin-1-yl-propyl]-4-phenyl-chromen-2-one::5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxo-3-(1-pyrrolidinyl)propyl]-4-phenyl-1-benzopyran-2-one::5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxo-3-pyrrolidin-1-ylpropyl]-4-phenylchromen-2-one::8-[3-keto-1-(4-methoxyphenyl)-3-pyrrolidino-propyl]-5,7-dimethoxy-4-phenyl-coumarin::MLS000879470::SMR000465530::cid_16746438

SMILES COc1ccc(cc1)C(CC(=O)N1CCCC1)c1c(OC)cc(OC)c2c(cc(=O)oc12)-c1ccccc1

InChI Key InChIKey=PROGRNRRJJYCNX-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50746   

TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataKi:  350nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataIC50:  9.82E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataIC50:  4.62E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataIC50:  4.32E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50746(5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed