BDBM508758 Method #3::US11071721, Example 3::US11071721, Example 36::US11607396, Example 36

SMILES F[C@H]1C[C@@H](c2ccccc2)n2nc(nc12)C(=O)N1CC(F)(F)C1

InChI Key InChIKey=PNTDDJXBRCPMCW-QWRGUYRKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 508758   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508758(Method #3 | US11071721, Example 3 | US11071721, Ex...)
Affinity DataKi:  4nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508758(Method #3 | US11071721, Example 3 | US11071721, Ex...)
Affinity DataKi:  4nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508758(Method #3 | US11071721, Example 3 | US11071721, Ex...)
Affinity DataKi:  9nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM508758(Method #3 | US11071721, Example 3 | US11071721, Ex...)
Affinity DataKi:  9nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent