BDBM510537 US11078182, Ex. 3.1

SMILES CN([C@H]1CCN(C1)C(=O)c1ccc(NC(C)(C)CCO)nc1)C(C)=O

InChI Key InChIKey=KPVHQUACMWDXFV-HNNXBMFYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510537   

TargetPantetheinase [22-493](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM510537(US11078182, Ex. 3.1)
Affinity DataIC50:  0.200nMAssay Description:0.1 nM of FLAG-tagged Vanin-1 (AA 22-493, T26I, produced internally) and test compounds are incubated at room temperature for 20 minutes in assay buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM510537(US11078182, Ex. 3.1)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human vanin-1 in whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPantetheinase(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM510537(US11078182, Ex. 3.1)
Affinity DataIC50:  200nMAssay Description:Inhibition of vanin-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed