BDBM514098 N-[(2S)-3-(3-Chlorophenyl)-1-[[(1S)-2-[[(3S)-5,5-difluoro-2-methyl-4,6-dioxo-6-(2,2,2-trifluoroethylamino)hexan-3-yl]amino]-1-(4-methoxyphenyl)-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-fluorobenzamide::US11059858, Example 52

SMILES COc1ccc(cc1)[C@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cccc(F)c1)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)C(=O)NCC(F)(F)F

InChI Key InChIKey=DJPRNIMMTIULHF-QKDODKLFSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514098   

TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514098(N-[(2S)-3-(3-Chlorophenyl)-1-[[(1S)-2-[[(3S)-5,5-d...)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent