BDBM515211 US11098058, Example 108::US11098058, Example 159::US11098058, Example 78

SMILES F[C@H]1C[C@@H](c2ccccc2)n2nc(cc12)C(=O)C1CC1

InChI Key InChIKey=ZVFQVMAYIWJCSR-JSGCOSHPSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515211   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM515211(US11098058, Example 108 | US11098058, Example 159 ...)
Affinity DataKi:  3.70nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM515211(US11098058, Example 108 | US11098058, Example 159 ...)
Affinity DataKi:  5nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM515211(US11098058, Example 108 | US11098058, Example 159 ...)
Affinity DataKi:  20nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent