BDBM515817 US11053225, Compound 89

SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1

InChI Key InChIKey=CLIUGIMDTBGMNI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515817   

TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515817(US11053225, Compound 89)
Affinity DataIC50:  0.0410nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515817(US11053225, Compound 89)
Affinity DataIC50:  16nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515817(US11053225, Compound 89)
Affinity DataIC50:  210nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent