BDBM515880 US11053225, Compound 182

SMILES CC(C)Cn1cc(cn1)-c1cnc(Nc2cc(F)cc(Cl)c2)nc1Nc1ccc2CCNCc2c1

InChI Key InChIKey=QLRMYWGPTHTIEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515880   

TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515880(US11053225, Compound 182)
Affinity DataIC50:  0.270nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515880(US11053225, Compound 182)
Affinity DataIC50:  650nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515880(US11053225, Compound 182)
Affinity DataIC50:  2.45E+3nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent