BDBM518586 US11124523, Example (+)-22

SMILES Cc1cccc(CNCC[C@]2(CCO[C@]3(CCOC3)C2)c2ccc(F)cn2)c1

InChI Key InChIKey=KDBYCIGWZXGKPW-DHIUTWEWSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 518586   

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataEC50:  0.100nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Rattus norvegicus)
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50:  1.88E+4nMAssay Description:To test the blocking effects of the compounds of the present disclosure on hERG potassium currents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50:  1.93E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM518586(US11124523, Example (+)-22)
Affinity DataIC50: >5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent