BDBM520288 N-[6′-Chloro-5-(cyclobutylmethyl)spiro[2,4-dihydro-1,5-benzoxazepine-3,1′-tetralin]-7-yl]sulfonyl-2-phenyl-acetamide::US11130769, Ex. No. 5

SMILES Clc1ccc2c(CCCC22COc3ccc(cc3N(CC3CCC3)C2)S(=O)(=O)NC(=O)Cc2ccccc2)c1

InChI Key InChIKey=VOFMXULSZNTXAG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520288   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM520288(N-[6′-Chloro-5-(cyclobutylmethyl)spiro[2,4-d...)
Affinity DataKi:  37.3nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent