BDBM520299 N-[(3S)-6′-Chloro-5-(cyclobutylmethyl)spiro[2,4-dihydro-1,5-benzoxazepine-3,1′-tetralin]-7-yl]sulfonyl-2-thiazol-2-yl-acetamide::US11130769, Ex. No. 16
SMILES Clc1ccc2c(CCC[C@]22COc3ccc(cc3N(CC3CCC3)C2)S(=O)(=O)NC(=O)Cc2nccs2)c1
InChI Key InChIKey=RRNWYCFSQMPWQU-NDEPHWFRSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 520299
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataKi: 9nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair