BDBM520301 (3R,6R,24S)-6′-Chloro-17,17-dioxo-spiro[8,22-dioxa-17λ{circumflex over ( )}6-thia-1,16-diazapentacyclo[16.7.2.1{circumflex over ( )}9,13.0{circumflex over ( )}3,6.0{circumflex over ( )}21,26]octacosa-9(28),10,12,18(27),19,21::US11130769, Ex. No. 18
SMILES Clc1ccc2c(CCC[C@]22COc3ccc4cc3N(C2)C[C@@H]2CC[C@H]2COc2cccc(CC(=O)NS4(=O)=O)c2)c1
InChI Key InChIKey=UONOINDJFXZPTC-TWVHRYOLSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 520301
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataKi: 1.40nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair