BDBM520308 (1S,1′R,2′R)-6-Chloro-3,4-dihydro-2H-spiro[naphthalene-1,3′-5,10-dithia-9-aza-1(5,7)-benzo[b][1,4]oxazepina-6(1,3)-benzena-3(1,2)-cyclobutanacyclodecaphan]-8′-one 10′,10′-dioxide::US11130769, Ex. No. 25
SMILES Clc1ccc2c(CCCC22COc3ccc4cc3N(C2)CC2CC[C@H]2CSc2cccc(CC(=O)NS4(=O)=O)c2)c1
InChI Key InChIKey=ITPKRFYAOROOSH-ZGPQHVOCSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 520308
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataKi: 9nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair