BDBM520498 (3R,6R,12S,22S)-6′-Chloro-12-methyl-15,15-dioxo-spiro[8,20-dioxa-15-thia-1,11,14-triazatetracyclo[14.7.2.03,6.019,24]pentacosa-16,18,24-triene-22,1′-tetralin]-10,13-dione::US11130769, Ex. No. 197
SMILES C[C@@H]1NC(=O)COC[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)S(=O)(=O)NC1=O
InChI Key InChIKey=WVDCGVIGFQBLKO-ULDCMCNTSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 520498
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataKi: <100nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair