BDBM520578 (3R,6R,7S,8E,22S)-6′-Chloro-7-[2-(3-fluoroazetidin-1-yl)ethoxy]-11,12,12-trimethyl-15,15-dioxo-spiro[20-oxa-15-thia-1,11,14-triazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16,18,24-tetraene-22,1′-tetralin]-13-one::US11130769, Ex. No. 275
SMILES CN1C\C=C\[C@H](OCCN2CC(F)C2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)S(=O)(=O)NC(=O)C1(C)C
InChI Key InChIKey=GBUASTABSMZWNZ-GSPAOZHHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 520578
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataKi: <100nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair