BDBM520597 US11130769, Ex. No. 294::[(3R,6R,7S,8E,15S,25S)-6′-Chloro-16,18,18-trioxo-spiro[23-oxa-18-thia-1,11,17-triazapentacyclo[17.7.2.03,6.011,15.022,27]octacosa-8,19,21,27-tetraene-25,1′-tetralin]-7-yl] N,N-dimethylcarbamate

SMILES CN(C)C(=O)O[C@H]1\C=C\CN2CCC[C@H]2C(=O)NS(=O)(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@@H]14)c3c2

InChI Key InChIKey=MJIKPGFZDJFXGQ-TXFVDOSGSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520597   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM520597(US11130769, Ex. No. 294 | [(3R,6R,7S,8E,15S,25S)-6...)
Affinity DataKi: <100nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent