BDBM520600 (23S)-6′-Chloro-16,16-dioxo-spiro[21-oxa-thia-1,6,9,15,27-pentazapentacyclo[15.7.2.13,6.19,12.020,25]octacosa-10,12::US11130769, Ex. No. 297

SMILES Clc1ccc2c(CCC[C@]22COc3ccc4cc3N(C2)CC2CCN(C2)C(=O)Cn2ccc(CC(=O)NS4(=O)=O)n2)c1

InChI Key InChIKey=JWARBWNJBBPODY-QOWRFBDLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520600   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM520600((23S)-6′-Chloro-16,16-dioxo-spiro[21-oxa-thi...)
Affinity DataKi: <100nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent